England have suffered a major setback ahead of Saturday’s Guinness Six Nations clash with Wales after Courtney Lawes was ruled out by an injury sustained in training.
Lawes was poised to continue at blindside flanker for the Cardiff showdown only to suffer an unspecified injury during Wednesday afternoon’s customary full-blooded training session.
The Northampton forward’s place in the back row goes to Mark Wilson, who fills the vacancy in the number six jersey after being dropped for the round-two victory over Italy.
The only other change to the XV that routed the Azzurri at Twickenham is Jamie George returning at hooker in place of Luke Cowan-Dickie.
Eddie Jones said: “Wales is a really special fixture and rivalry. There is a long history between the two nations and the game means a lot to both countries.
“We know we’ll be up against a strong Welsh challenge on Saturday, but we’ve worked really hard in training this week and have got a very good team to face it.
“We want to show people what we are capable of, keep building our performances and the best is yet to come from this England team.”
15. Elliot Daly (Saracens, 49 caps)
14. Anthony Watson (Bath Rugby, 48 caps)
13. Henry Slade (Exeter Chiefs, 36 caps)
12. Owen Farrell (Saracens, 90 caps)
11. Jonny May (Gloucester Rugby, 63 caps)
10. George Ford (Leicester Tigers, 74 caps)
9. Ben Youngs (Leicester Tigers, 106 caps)
1. Mako Vunipola (Saracens, 64 caps)
2. Jamie George (Saracens, 56 caps)
3. Kyle Sinckler (Bristol Bears, 41 caps)
4. Maro Itoje (Saracens, 45 caps)
5. Jonny Hill (Exeter Chiefs, 6 caps)
6. Mark Wilson (Newcastle Falcons, 20 caps)
7. Tom Curry (Sale Sharks, 30 caps)
8. Billy Vunipola (Saracens, 58 caps)
16. Luke Cowan-Dickie (Exeter Chiefs, 28 caps)
17. Ellis Genge (Leicester Tigers, 25 caps)
18. Will Stuart (Bath Rugby, 10 caps)
19. Charlie Ewels (Bath Rugby, 18 caps)
20. George Martin (Leicester Tigers, uncapped)
21. Ben Earl (Bristol Bears, 10 caps)
22. Dan Robson (Wasps, 9 caps)
23. Max Malins (Bristol Bears, 5 caps)